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these cases demonstrated a patchy pseudo map-like glutamine synthetase pattern along with the expression of serum amyloid-associated protein

Therapeutic targeting of the redox balance is regarded as an effective strategy for treating oxidative stressrelated diseases, such as supplementation of direct antioxidants and enhancement of endogenous antioxidant defense network

A previous study reported that the upregulation of claudin-2 was associated with increased gut permeability

SIM1 induced the rapid degradation of BRD4 with a DC 50 of ~4.2 nM after 2 h treatment (Fig

Additionally, inhibition of CD38 in the AD mouse model restored NAD + levels, decreased mitochondrial ROS production and plaque depositions in the hippocampus and cortex, and improved cognitive abilities 158

after the resolution of neuroinflammation, astrocytes form glia limitans perilaesiones 185
