cowan human glutaredoxin 3 glutathione 3: multiple domains for a unique function Glutathione/Glutaredoxin in Cellular Redox Homeostasis

Both excesses and deficiencies of certain nutrients, as well as exposure to heavy metals, toxins, and endocrine disruptors, can disrupt immune tolerance

10.1002/(SICI)1097-4547(19970315)47:6 3.0.CO;2-Z 9 AntonicA.DottoriM.MacleodM

[DOI] [PubMed] [Google Scholar] 246.Gadde KM, Allison DB, Ryan DH, et al

Activation of promoter activity of the catalytic subunit of -glutamylcysteine ligase (GCL) in brain endothelial cells by insulin requires antioxidant response element 4 and altered glycemic status: implication for GCL expression and GSH synthesis

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Thus, the current finding of reduced mPFC GABA levels in high schizotypy participants is broadly consistent with diminished GABAergic regulation from the mPFC shown in the MAM model of psychosis, but whether this is due to a reduced density of parvalbumin interneurons (as shown in the animal model) cannot be established using MRS