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This work was supported by the Natural Science Foundation of Henan Province (General Science Foundation Project) (222300420558), National Natural Science Foundation of China (82200705), 2022 Henan Medical Science and Technology Joint Construction Project (LHGJ20220338), Henan Province Key R&D and Promotion Project (222102310007), Henan Province Science and Technology Project (212102310631), and Henan Province Medical Science and Technology Key Project (Guiding Plan) (SBGJ202002106)

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The rabbits were divided into five random groups of 24 rabbits each, with 8 replicates per group (3 rabbits each)

SAPH integrates the advantages of both natural and synthetic biomaterials while overcoming their limitations, allowing for the modulation of mechanical and structural properties through peptide sequence modification

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