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This process is accompanied by the downregulation and diminished nuclear translocation capability of the key transcription factor FOXC2, weakening its normal regulatory control over LECs

doi: 10.1038/oby.2011.115

In particular, reduced GST activity as compared to control subjects was described in all brain areas and ventricular CSF in postmortem AD patients, suggesting a role of these enzymes in the pathogenesis of the disease 51

Today 20 (9), 11431151

Ultrastructural and histochemical study of the motor end plates of the intrinsic laryngeal muscles in amyotrophic lateral sclerosis
doi:10.1074/jbc.M115.646984
