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New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose

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Due to the susceptibility of intracellular ROS and immunotherapeutic drugs to degradation in vivo, effectively delivering genes or small-molecule drugs to macrophages remains a challenge

This modification was confirmed through immunoblotting and isotope labeling experiments, demonstrating that it originates from intracellular glycolysis [3]

5 Targeting gut microbiota for acute liver injury Various factors, such as drugs, toxicants, and viral infections, produce hepatotoxicity and lead to ALI, which severely damages liver function and inevitably damages human health (76)

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