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Another metabolic product of intestinal bacteria, urolithins (UA), is produced through the conversion of dietary ellagitannins and ellagic acid by specific gut microbiota

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Their work combined in vitro assays (testing 3-hydroxybutyrate on rat hippocampal neurons and five glioma cell lines) with in vivo orthotopic xenograft mouse models

10.1038/s41590-022-01291-2 36 GuoJ.ZhuJ.WangQ.WangJ.JiaY