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BPC-157 (Body Protection Compound) is a synthetic 15-amino acid peptide derived from a fragment of a protein found in human gastric juice

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Citing significant, unresolved safety risks, a total lack of robust human clinical efficacy data, and grave concerns over immunogenicity and peptide-related impurities, the FDA officially designated 19 of the most popular therapeutic peptidesexplicitly including BPC-157, TB-500 (Thymosin beta-4 fragment), and injectable GHK-Cuas Category 2 bulk drug substances

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Interestingly, we observed the highest density of Gdf11 expression in the habenula and our results align with a recent habenula focused single-cell RNA-sequencing paper which reported Gdf11 within the top 25% of highly expressed genes in the region [25]