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[Google Scholar] 185.Han F, Wang T, Liu G, Liu H, Xie X, Wei Z, Li J, Jiang C, He Y and Xu F, Adv

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In response to oxidative stress, NRF2 dissociates from KEAP1, translocates to the nucleus, and activates genes encoding antioxidant enzymes (e.g., superoxide dismutase SOD) and glutathione synthesis enzymes, reducing reactive oxygen species (ROS) and mitigating oxidative damage (21)

Antioxidant as an adjunct to root surface debridement have improved the periodontal therapy outcome in periodontitis patients by overcoming delayed wound healing induced by imbalance in redox status