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The GSH substrate binds in an extended conformation at the interface between two subunits of the trimer supported by new in vitro mutagenesis data
The results revealed a significant reduction in overall HMGB1/2 DNA-binding signals in HCMECs (Figure 5A)
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278 It can be caused by diverse virus families ranging from DNA (i.e., HBV, EBV, HSV-1) to RNA viruses (i.e., HCV, RSV, DENV, Influenza, ZIKA, HIV)
In addition, the NADPH oxidase (NOX) family can generate ROS by means of specific enzymes ( 2 )
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