foxo4 dri peptide senolytic 2024 Frontiers Peptide inhibitors targeting FOXO4-p53 interactions
Description
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Store in a cool, dry place away from direct light to maintain optimal stability
Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors
The compound functions as a synthetic D-retro-inverso peptide carrying a shortened version of the FOXO4 segment that binds to p53, acting as a competitive inhibitor of this critical protein-protein interaction
