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Our screen unveiled 38 chemically diverse electrophiles with senolytic activity

10.1016/j.ebiom.2021.103560 EBioMedicine 94 ShaoZ.TuS.ShaoA
The possibility of Pt(IV) complexes inducing the formation of reactive oxygen species (ROS) has been considered only recently 41,42
Alzheimer's Res
Because it relies on the pituitary's own machinery, the GH release it produces follows the body's natural pulsing rhythm rather than overriding it

Knockdown of ARNTL2 significantly decreases the expression levels of Nrf2, SLC7A11, and CDGSH iron-sulfur domain protein 1 of lung adenocarcinoma cells, and increases the sensitivity to ferroptosis
