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[DOI] [PubMed] [Google Scholar] 148.Testai L., Martelli A., Flori L., Cicero A., Colletti A

During the course of disease, autoantigen modification activates innate and adaptive immune responses

[DOI] [PubMed] [Google Scholar] 50.Paulis G., Brancato T

The instruction also extends to maintenance of normal blood LDL-cholesterol concentrations, contribution to normal spermatogenesis, and/or decreasing free fatty acids in blood during pregnancy

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It is widely known that mitochondrial dysfunction (high ROS production, apoptotic cells, decreased m, and low cellular ATP levels) boosts the pathogenesis of KOA because it involves lipid homeostasis and cytokine release and promotes cell apoptosis [14, 15]