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Published research indexed on PubMed has investigated BPC-157s interaction with several biological pathways

Antioxidant expression is either not induced or is declined, allowing increased ROS expression that positively promotes tubulointerstitial fibrosis via necrosis, apoptosis, epithelial-mesenchymal transition, interstitial fibroblast activation, endothelial cell proliferation, and pericytes transformation [17,209,229,230]

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Moreover, IS is also positively correlated with circulating tissue factor (TF) levels induced by the aryl hydrocarbon receptor (AhR) activation in endothelial cells and peripheral blood mononuclear cells (PBMCs) [57]

Koca et al