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Yuan, M
doi: 10.1002/biof.1363 70 Corts-ChitalaMFlores-MartnezHOrozco-vilaILen-CamposCSurez-JacoboEstarrn-EspinosaMet al
The most parsimonious hypothesis is simply that this is a case of a viral protease targeting a cellular gene for cleavage, for which there are abundant precedents, including the proposed M pro targeting of TRMT1 and HDAC2 ( Functional Effects of M PRO in Transfected Cells are Consistent With GPX1 Knockdown As detailed above, the original 2003 SCoV M pro has essentially identical substrate sequence specificity as that of SCoV2
Gastroenterology 137 , 14891497 (2009)
Hughes and Smith, 2007)
From 205 in clinic
