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CJC-1295 (without DAC) stands as an exceptional example of rational peptide design and pharmaceutical development, representing a sophisticated molecular tool that has transformed growth hormone research by providing researchers with the ability to enhance and extend natural GHRH signaling while preserving essential physiological pulsatile patterns

Li et al used tetrahedral framework nucleic acid (tFNA) to synthesize tFNA-Cur, a nanoparticle that can deliver the natural compound curcumin to the bone marrow, thereby enhancing the bioavailability and stability of curcumin

PMID: 8426207

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Snchez-Gmez et al., 2010)