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H., et al., Nanotechnological Synergy of Mangiferin and Curcumin in Modulating PI3K/Akt/mTOR Pathway: A Novel front in Ovarian Cancer Precision Therapeutics, Frontiers In pharmacology 14 (2023): 1276209

As the immune system takes priority in survival, insufficient glutathione may express itself as fatigue since skeletal muscles cannot sustain normal aerobic metabolism

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(2) Reduced acidification in the stomach, due to aging or drugs (Proton Pump Inhibitors or H 2 -Receptor antagonists) may lead to reduced release of B 12