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However, we did not observe case-control differences (Supplementary Fig

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L-carnitine is a nutrient and dietary supplement that plays a crucial role in the metabolism of fat

Cultures were fed an additional 0.5% v/v methanol at 24 h post-induction

Furthermore, others such as the inhibition or activation of enzymes that participate in the carcinogenesis process could reduce the proliferative and metastatic capacity of tumor cells

As described, ABX-induced intestinal dysbiosis results in the altered microbial BA metabolism, which destroys the homeostasis between BA synthesis in the liver and BA metabolism in the intestine, restricts the farnesoid X receptor (FXR)/fibroblast growth factor 15 (FGF15) signaling axis in enterocytes with the conjugated BAs being an effective inhibitor of FXR, and further undermines the interplay of FGF15 with fibroblast growth factor receptor 4 (FGFR4) in the hepatocytes (114)