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Apart from some reports with elevated CRP in lung squamous cell carcinoma and large cell carcinoma, CRP levels have predicted a lack of response to treatment in advanced lung adenocarcinoma individuals with or without EGFR mutations, thus serving as a prognostic marker and objective indicator for clinical practice [807]

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Although thematic overlaps exist, each country has developed distinct research focus areas supported by specific preclinical models

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Pagetoid extension into the epidermis, when present, tends to be extensive and to a high level in melanomas, while minimal or absent in nevi
