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Both the 12( Z )- and 11( E )-isomers are PPAR agonists, while the 12( Z )-isomer is recognized by GPR40

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EMBO J 21:16281637 [DOI] [PMC free article] [PubMed] [Google Scholar] Chaipatikul V, Erickson-Herbrandson LJ, Loh HH, Law PY 2003 Rescuing the traffic-deficient mutants of rat -opioid receptors with hydrophobic ligands