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Drug concentrations were determined and loss of parent relative to negative control samples containing no microsomes was calculated

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For example, oxidative stress-induced microRNA-9/9* has been implicated in the MELAS phenotype, while downregulation of microRNA-181a/b, which promotes MQC through the activation of mitochondrial biogenesis and mitophagy, has shown protective effects on RGCs in an LHON mouse model

Adenosylcobalamin does participate in fatty acid metabolism through methylmalonyl-CoA mutase