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Gastric and intestinal protection is the second major research stream, consistent with the compound's gastric-juice origin

Impaired TRPM3-Dependent Calcium Influx and Restoration Using Naltrexone in Natural Killer Cells of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients. Journal of Translational Medicine, vol

Because of this caveat, it cannot be said conclusively that PDI is more sensitive to oxidative damage or degradation, however, it is a plausible mechanism

1992;263:G6068

Thereby, the high variety between studies, in for example the IVD degeneration model, followup period or painbehavioral assays, renders it problematic to present a systematic literature review of preclinical work describing the effects of CDLBP therapy on neuronal growth, effects on nociception and/or pain