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In the component of primary outcome, persistent 50% eGFR decline from baseline was significantly reduced in semaglutide group (HR 0.73, 95% CI 0.590.89)

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Besides, the annexin V/PI apoptosis assay showed that LPS significantly induced the early and late apoptosis of RAW264.7 cells and GSK872 markedly decreased the late apoptosis rate ( Supplementary Figure 6 )

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