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Neurological sequel of chronic kidney disease: from diminished acetylcholinesterase activity to mitochondrial dysfunctions, oxidative stress and inflammation in mice brain

As CSC-targeted therapy moves toward clinical application, a multidisciplinary approach that integrates systems biology, synthetic biology, immunotherapy, and machine learning-driven precision medicine is essential

Kivipelto M, Mangialasche F, Ngandu T

A 2020 study demonstrated that the AEDG peptide increased expression of neurogenic differentiation markers (Nestin, GAP43, -Tubulin III, Doublecortin) by 1.61.8-fold in human mesenchymal stem cells (9)

Semax is the second most clinically validated, with pharmaceutical approval in Russia for stroke recovery
3.3 Characterization of PTX-CSNPs The physicochemical properties of PTX-CSNPs were evaluated using advanced analytical techniques
