methitrexate plus glutathione Synthesis of glutathione-responsive, amphiphilic methotrexate-based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer Glutathione 500 mg Plus –

Key outstanding questions are cellular/ tissue specificities and activities against GSH compared to GS-conjugates or GSSG, which can be considered as a glutathioneglutathione conjugate

Glutathione is an abundant intracellular thiol (a compound containing a sulfhydryl group) and low molecular weight tripeptide found in living cells.* Serving as an antioxidant in all types of tissues, the antioxidant functions of glutathione include recycling vitamins C and E to their antioxidant form to minimize oxidative stress.*

doi: 10.1016/j.jneuroim.2004.02.011

The clearest hypothesis is that GSH synthesis is required for liver function

Wie sicher ist Glutathion

Current studies on IV glutathione have failed to evaluate the long-term safety profile of its use [55]