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MMNST occur in some patients with Carney Complex, a rare syndrome associated with PRKAR1A mutation, cardiac and skin myxomas, endocrine and gonadal neoplasms, variable endocrine manifestations such as Cushing syndrome or acromegaly, increased lentigines, and a type of blue nevus known as pigmented epithelioid melanocytoma [5, 6]

doi: 10.1016/0891-5849(94)90197-x

Oxidative stress induces cardiomyocyte apoptosis (programmed cell death) and necrosis [84]

Since new collagen is formed in the areas treated with Cellulaze and the structures under the skin are altered, the results are lasting

HUMAN ETHICS APPROVAL DECLARATION Authors declare human ethics approval was not needed for this study

Furthermore, Black and Hispanic individuals are often diagnosed with more aggressive types of melanoma, including acral and mucosal melanoma