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The pSpCas9(BB)2A-GFP (PX458) was a gift from Medhi Khaled (Institut Gustave Roussy)

This vicious cycle of energy depletion, anaerobic shift, and lactic acidosis creates a biological trap that keeps patients locked in a state of chronic exhaustion, highlighting the critical need to restore aerobic mitochondrial function
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[DOI] [Google Scholar] 274.Ross A.B., Mallard W.G., Helman W.P., Buxton G.V., Huie R.E., Neta P

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