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Effects on Neurodegenerative Diseases The consumption of antioxidant-rich diets was shown to alleviate the harmful impact of neurodegenerative diseases (Alzheimers disease, Parkinsons disease, depression multiple sclerosis, Huntingtons disease, etc.), probably due to the potential neuroprotective activity of polyphenols through the activation of signaling pathways related to protein kinases such as Keap1/Nrf-2/ARE, the main protective pathway against ROS damage [159]
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Nrf2-Keap1-ARE-NQO1 signaling attenuates hyperoxia-induced lung cell injury by inhibiting apoptosis
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Ann N Y Acad Sci 1478(1):317
[DOI] [PMC free article] [PubMed] [Google Scholar] 420.Abu-Amero K.K., Kondkar A.A., Mousa A., Osman E.A., Al-Obeidan S.A
