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In the event of a stroke, the depletion of adenosine triphosphate (ATP) triggers the ischemic cascade, which ultimately leads to the accumulation of calcium within the cells, the failure of the ion pump, and the glutamate-induced cell excitotoxicity (17)

Furthermore, their different chemical composition compared to the peptide chains of antibodies allows for site-specific modification, making them suitable sites for conjugation

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EBioMedicine 73 (2021)

Despite the well-documented advantages of SAL, research gaps persist regarding optimal dose, long-term safety, and comprehensive effectiveness comparisons in clinical environments

(Cystine is the oxidized form of cysteine.) The xCT antiporter consists of two subunits that are encoded by the SLC7A11 and SLC3A2 genes
