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The effects of vitamin E (200 mg) supplementation, in combination with vitamin C (300 mg), and -carotene at various concentration (16.7, 8.4, 5.6, or 0 mg/day), compared with those of vitamin E alone, were evidenced in a study conducted on 276 elderly subjects aged between 60 and 75 years

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A key finding from a 2005 genome-wide association study (GWAS) identified an intronic variant in CFH, specifically the Y402H polymorphism, [61] where tyrosine (Y) is replaced by histidine (H) at position 402

Global hypoxia affects the electron transport chain, fatty acid beta-oxidation and other metabolic pathways essential for mitochondrial energy production