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In addition to cytochrome c , other IMS proteins are also mobilized and released into the cytosol where they promote or counteract caspase activation and hence cell death (Li et al., 2001

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The resistant parasites also exhibit improved tolerance to host defense mechanisms, such as nitrosative stress, and evade immune responses through increased interleukin-10 (IL-10) production, which facilitates immune evasion ( FIGURE 3 In addition to drug efflux and membrane adaptations , L

Comments about each stage are presented under the diagram

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