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[DOI] [PMC free article] [PubMed] [Google Scholar] 975.Soleimani Z., Amighi F., Vakili Z., Momen-Heravi M., Moravveji S.A

In summary, the accumulation of TMAO will not only increase oxidative stress and endothelial cell damage and permeability but also lead to an increase endothelial-derived NOS expression ( Vascular Calcification: TMAO Activates the NLRP3 Inflammasome and NF-B Signaling Pathway in Vascular Smooth Muscle Cells (VSMCs) Vascular calcification (VC) is a phenomenon of disseminated deposition of mineral content within the medial layer of arteries

It has even been suggested that prevention for those who are at high risk for PD should begin during childhood [27]

2013 Jul;31(4):293-300 (Ver) Riaz M, Mahmood Z, Shahid M, Saeed MU, Tahir IM, Shah SA, Munir N, El-Ghorab A

Statistical analysis was performed using SPSS software (version 22

The potential of TMAO to result in atherogenic effects is linked to alterations in cholesterol and bile acid metabolism, inflammatory pathway activation, and foam cell formation promotion