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Conversely, in patients with anorexia nervosa, even supra-physiologic GH doses (mean maximum daily dose: 1.4 mg/day) may not be sufficient to normalize IGF-I levels (61) indicating the important role of hepatic GH sensitivity in successful IGF-I generation

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doi: 10.1038/nbt.2508 60 JiangY.ZhengW.TranK.KamilarE.BariwalJ.MaH.et al

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The mitochondrial carnitine shuttle system transports activated long-chain fatty acids from the cytosol inside the mitochondria for subsequent beta-oxidation [1]