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Over-reactive warheads lead to significant non-specific covalent protein modifications - a major cause for immunotoxicity and idiosyncratic hypersensitivity reactions, as represented in -lactam-induced allergic reactions [108,109]

doi: 10.1016/S0022-3999(01)00315-4 Summary Keywords Sensewear armband, myalgic encephalomyelitis/chronic fatigue syndrome, vitamin B12 nasal drops, vitamin B12 serum concentration, RAND 36 questionnaire Citation van Campen CLMC, Riepma K and Visser FC (2019) Open Trial of Vitamin B12 Nasal Drops in Adults With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Comparison of Responders and Non-Responders

In contrast to our findings, a placebo-controlled trial using silymarin in patients with liver cirrhosis of various etiologies showed that treatment of patients with silymarin had a higher 4-year survival rate than patients who received placebo

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