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Popular biguanides like chlorhexidine have been in use and under research since the mid-20th century (Davies et al., 1954)

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Given that studies have shown that saphenous vein of humans and animals exhibits an active myogenic response and that stretch-induced AT1R and TRPC channels signaling mechanism are responsible for the myogenic response in arteries, it remains, however, to delineate the underlying signaling pathways and the identity of mechanosensors of myogenic response in human superficial veins of the lower extremities

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The lyophilized product should be stored refrigerated and protected from light and moisture
