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By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1)

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Unlike retinoids or exfoliating acids, they do not typically cause irritation, peeling, or photosensitivity

They activate different second messenger systems

AOD-9604, short for Anti-Obesity Drug-9604, is a synthetic analog of the human growth hormones lipolytic (fat-burning) region