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Vaillant reports that in 1979 Switzerland hosted the first World Climate Conference to foresee and prevent potential man-made changes in climate that may be adverse to the well-being of humanity. Leading to that conference, the American Petroleum Institute, Exxon, and most other major oil companies had established a collaborative and objective research team, which included federal scientists, called the CO2 and Climate Task Force
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While this strategy reduces development risks, it may also miss opportunities to discover revolutionary therapeutic methods
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When the anti-CEACAM5 ADC SAR408701 showed limited efficacy or resistance, CAR-T cells targeting the same antigen could still effectively induce cytotoxic responses and significantly inhibit tumor growth in vivo [154]
