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By addressing both the biological rationale and methodological limitations of existing studies, this review provides insight that could be used as a reference to inform clinical decision-making and support the development of robust, evidence-based guidelines for tinnitus management

Supplementing patients with L-GSH has been shown to increase IL-2, IL-12, and IFN- and decrease IL-6, IL-10, and TGF-, thus resulting in an overall more appropriately balanced immune response to pathogens