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Description
Cancer-associated IDH1 promotes growth and resistance to targeted therapies in the absence of mutation
There are many documented clinical cases, all of them varied, with a multitude of symptoms, combinations of several of them, and uncertain onset, and with relatively good responses to treatment, but sometimes with very serious consequences if action is delayed: pancytopenia, organ failure, partial or permanent vision loss that is not recovered, heart attacks, and death

TB-500, by contrast, works more systemically

(PubMed) Lin J, Lee IM, Cook NR, et al
Studies with genetically encoded sensors for Ca 2+ cycling and SV exocytosis revealed the core roles of mitochondria in presynaptic Ca 2+ clearance [54, 55]

A study on the BPH rat model reported that treatment with N
