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An update on nondopaminergic treatments for motor and non-motor symptoms of Parkinsons disease

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This inflammatory state, termed inflammaging, is one of the most consistent features of biological aging and correlates with nearly every major age-related disease [8]

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Since the impressive improvement noted with IVIg in the 3-month controlled trial conducted more than 20 years ago (29), IVIg has been used monthly, for the chronic management of stiff-person syndrome, even if sometimes there is no objective evidence that it continues to be effective based on declining benefits before each monthly infusion

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-AASA accumulation is the metabolic signature of a deficiency in -AASA dehydrogenase observed in patients with pyridoxine-dependent epilepsy

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