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Enhancing glucose metabolism via gluconeogenesis is therapeutic in a zebrafish model of Dravet syndrome

Gudkov, p16(Ink4a) and senescence-associated -galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli

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When ADH5 expression is reduced in certain organs and cell types in individuals with dominant-negative ALDH2*2 alleles, the ability to metabolize endogenous formaldehyde may be significantly reduced, possibly resulting in endogenous formaldehyde accumulation

disorder, detoxification, glutathione).

Superoxide dismutase and catalase are the two major scavenging enzymes that remove the toxic free radicals in vivo