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The cell contains millimolar concentrations of GSH (up to 10 mM) that is maintained in this reduced form by a cytosolic NADPHdependent reaction catalysed by glutathione reductase
Thus treatment with ALCAR during the first 48 hours after HI on postnatal day 7, or after TBI on day 2122 led to long-term protection of the ipsilateral hemisphere and improved behavioral outcome [12, 39]
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Franklin RA, Liao W, Sarkar A, Kim MV, Bivona MR, Liu K, Pamer EG, Li MO
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