ascorbate and glutathione the heart of the redox hub Heat shock induces cross adaptation to aluminum stress through enhancing ascorbate-glutathione cycle in wheat seedlings The ascorbate–glutathione cycle—a major antioxidant

10.1016/j.pnpbp.2010.03.005 Prog

Nitric oxide ultimately leads to the formation of RNS (reactive nitrogen species) which is known to cause mitochondrial damage and is therefore suggested to be a critical agent in chondrocyte function and apoptosis

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S., Dudycha, S

Glutathione undergoes a reaction with the toxic substances, facilitated by enzymes such as glutathione S-transferases, to form a conjugate known as a glutathione adduct, which is then further metabolized in the liver to form mercapturic acid, a water-soluble compound that can be easily excreted through the urine