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Description
Macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2 phenotype
This modification can silence key metabolic genes, affecting pathways such as glycolysis, the tricarboxylic acid (TCA) cycle, and lipid metabolism
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Systolic blood pressure may be elevated, and hepatomegaly or splenomegaly may be observed (16)
Before looking at how they interact, it is helpful to understand what each of these does on its own
