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J Neurol Sci 290:4147 Bame M, Pentiak PA, Needleman R, Brusilow WS (2012) Effect of sex on lifespan, disease progression, and the response to methionine sulfoximine in the SOD1 G93A mouse model for ALS

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Three mechanistic explanations, not mutually exclusive: Signalling cascade persistence: BPC-157 activates VEGFR2 and FAK-paxillin pathways whose downstream effects (angiogenesis, fibroblast migration, collagen remodelling) unfold over days to weeks after initial receptor engagement

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