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Changes in serum cobalamin by supplementation route and dosage Across 35 comparisons, the mean percentage increase in serum cobalamin following supplementation was approximately 293%, confirming the overall effectiveness of vitamin B12 interventions (Supplementary Table S4)

PLoS Biology 12 (6), e1001874

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The primary outcome measure was the ACR20 response at 24 weeks, with ACR50/70/90, DAS28, EULAR response criteria, and time to ACR20 as secondary outcome measures

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