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The pre- and post-treatment stainings for all six subjects show statistically significant reduction (one-tailed, paired student t test, p = 0.028, Fig

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Methionine is a signal of amino acid sufficiency that inhibits autophagy through the methylation of Pp2a

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Exclusion criteria 1 - Patients with prior malignancy or present with metastatic malignant manifestations were not included in the present study