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These examples illustrate that global metabolic modulation can, to some extent, curtail tumor glucose availability to tumors, impacting their expansion

Such proteins usually contain amino acid sequences that direct the proteins to their final locations

However, when SOD activity increases, the enhanced levels of H 2 O 2 trigger the upregulation of CAT [11] and/or GPx [12], with a final antioxidant balance as a compensatory and defense response strategy

Lipoxidase and the Autoxidation of Unsaturated Fatty Acids

pp.36-44, 2008

Once activated, NF-B and Nrf2 are translocated to the nucleus, where they enhance the gene expression of pro-inflammatory mediators and detoxifying and antioxidant enzymes, such as HO-1 (Gur et al