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Finally, we discuss emerging strategies to interrogate and modulate this circuit using integrated omics, CRISPR-based screening, and pharmacological approaches, emphasizing the need for context-aware and temporally controlled metabolic interventions to enhance T cellbased immunotherapies in solid tumors

Hampl R, Strka L

575 In SAMP8 mice, salidroside upregulates SLC7A11 and GPX4 protein expression through activating Nrf2/GPX4 axis, reduces iron deposition and ACSL4 protein expression, thereby inhibiting ferroptosis and A accumulation, and alleviating cognitive impairment

Stresses 2(1):5364 [Google Scholar] Di Marzo N, Chisci E, Giovannoni R (2018) The role of hydrogen peroxide in redox-dependent signaling: homeostatic and pathological responses in mammalian cells

71, 16351642.10.1046/j.1471-4159.1998.71041635.x 20 Bar AmO.AmitT.YoudimM

Turner, P