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Over this direct action, melatonin can further activate melatonin (MT) 1 and MT2 receptors (Fig

It has been speculated that the accumulation of ROS, leading to lipid peroxidation, is primarily responsible for ferroptosis

Ding Y, Ye B, Sun Z, Mao Z, Wang W

4 Postbiotic substances include enzymes, bioactive peptides, short-chain fatty acids, antimicrobial peptides, polysaccharides, cell surface proteins, vitamins, plasmalogens, organic acids, and other compounds

Notably, natural compounds as potential ferroptosis inhibitors warrant further systematic investigation and high-quality clinical validation to confirm their safety and efficacy

Common side effects may include mild gastrointestinal discomfort, such as nausea or diarrhea, and occasional skin reactions like rash or itching at the injection site