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It works intracellularly by inhibiting NNMT to preserve NAD+ and shift adipocyte metabolism a completely different mechanism, with different research read-outs
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This happens more often in the thigh than the abdomen because the thigh has a denser vascular network in some areas
Bypass surgery itself removes areas that produce necessary co-factors for absorption, which is compounded by faster gut transit time, which lessens what can be extracted from the digestive process
